The objective of this stusy was to examine the associations of acetaminophen use during pregnancy with children's risk of autism, attention-deficit/hyperactivity disorder (ADHD), and intellectual disability. Findings suggest that acetaminophen use during pregnancy was not associated with children's risk of autism, ADHD, or intellectual disability in sibling control analysis. This suggests that associations observed in other models may have been attributable to familial confounding.

https://pubmed.ncbi.nlm.nih.gov/38592388/

References

  1. Lichtenstein P, Tideman M, Sullivan PF, et al. . Familial risk and heritability of intellectual disability: a population-based cohort study in Sweden. J Child Psychol Psychiatry. 2022;63(9):1092-1102.

  2. Subramanian A, Azcoaga-Lorenzo A, Anand A, et al. ; MuM-PreDiCT Group . Polypharmacy during pregnancy and associated risk factors: a retrospective analysis of 577 medication exposures among 1.5 million pregnancies in the UK, 2000-2019. BMC Med. 2023;21(1):21.

  3. Havdahl A, Wootton RE, Leppert B, et al. . Associations between pregnancy-related predisposing factors for offspring neurodevelopmental conditions and parental genetic liability to attention-deficit/hyperactivity disorder, autism, and schizophrenia: the Norwegian mother, father and child cohort study (MoBa). JAMA Psychiatry. 2022;79(8):799-810.

Categories

Child Health  Maternal/Fetal health during pregnancy  Newborn and Infants  

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